Affichage des articles dont le libellé est Sickle cell. Afficher tous les articles
Affichage des articles dont le libellé est Sickle cell. Afficher tous les articles

jeudi 29 mai 2014

Sickle cell anemia





Sickle cell anemia is an inherited blood disease. It is particularly common in populations from sub-Saharan Africa, the Caribbean, India, the Middle East and the Mediterranean basin.

The characteristics of the different levels of the phenotype of sickle cell disease are:

- At the organic level: severe anemia, weakness, respiratory disorders, heart attack and blood (blood circulation is Unusual).

- At the cellular level: the low number of red blood cells, Change its shape (crescent, or sickle), this latter leads to the blockage of blood vessels and thus non saturate tissue of blood

- At the molecular level: Hemoglobin in the lack of oxygen is less soluble, forming a solid grid of fibers in the cytoplasm of erythrocytes.